High Content Screening Analysis

High content screening hcs also known as high content analysis hca or cellomics is a method that is used in biological research and drug discovery to identify substances such as small molecules peptides or rnai that alter the phenotype of a cell in a desired manner.

High content screening analysis.

High content analysis hca high content analysis is a principle methodology for so called phenotypic screening in drug discovery and development process. With an unprecedented flatness whole plate and intra well these microplates are ideal for high resolution cellular imaging applications. Originally developed as a complementary technology to traditional biochemical high throughput screening hts in drug discovery today high content screening. For assay development and screening of non imaging assays refer to assay development and high throughput screening.

Assessing a vast number of compounds is time consuming therefore acquiring a large number of high resolution cellular images with fast scanning speed is critically important for drug screening. Corning glass bottom and cyclic olefin copolymer coc film bottom high content screening microplates deliver high optical quality for cell based assays. The hypercyt high throughput ht flow cytometry sampling platform uses a peristaltic pump in combination with an autosampler and a novel approach to data collection to circumvent time delay bottlenecks of conventional flow cytometry. This approach also dramatically reduces the amount of sample aspirated for each analysis typically requiring 2 μl per sample while making.